The SAMHSA Drug-Free Workplace Toolkit offers employers and prevention professionals actionable resources to design, implement, and sustain drug-free workplace policies and programs that support health, safety, and productivity. It includes guidance on assessing workplace needs, developing tailored policies, planning and launching prevention initiatives, providing education and supervisor training, and evaluating program outcomes, all aimed at reducing substance misuse and creating supportive organizational environments. This toolkit supports the prevention workforce by offering evidence-informed strategies that can be integrated into workplace health promotion efforts and broader community prevention planning.